Changes of electrocardiograms and heart morphology of animals with different resistance to hypoxia under influences of stress

Stress is a process that increases person’s adaptive capacity and leads to the various diseases, such as hypertension, coronary artery disease, heart attack, cardiac arrest, stroke, mental disorders depression anxiety even sudden death. Individual response stress may depend on age, gender, features of autonomic regulation, state central nervous system, endocrine systems, higher activity. With excessive stress, work internal organs disturbed, in particular, cardiovascular system. Determination damaging effect system individuals with different reactivity will contribute development individual correction methods. The aim study was analyze changes electrocardiograms (ECG) morphological feachers after animals resistance hypoxia. Material methods investigation. Experiments were performed 48 Wistar rats, high low hypoxia (HRH, LRH), aged 5–6 months. Animals divided into two groups – control experimental (after immobilization stress). Individuals selected by method V. Ya. Berezovsky. modeled three one-hour which immobilized their backs an interval 24 hours between each stressful episode. Investigation we did third immobilization. Under anesthesia registrated ECG taken for Sections stained hematoxylin eosin. Results. In examining HRH LRH animals, no significant difference analyzed indicators established. last 1 hour three-time rats noted increase rate, decrease duration RR interval, amplitude R wave, QTc T deviation ST segment from isoline. caused PQ When comparing parameters НRH found smaller P value greater Physiological can also connected feaches. Conclusions. functional histological properties heart, depends interval. Indxes grater rats. Mophological animals.